INDICATIONS FOR USE
A combined drug containing a plant-derived component indole-3-carbinol, which has an antiproliferative effect, normalizes the balance of estrogen and prevents the development of estrogen-dependent diseases. Indole-3-carbinol induces processes of apoptosis (programmed death) of transformed cells, including diseases associated with the human papillomavirus. It has a selective effect on cells with a high proliferative signal.
Indol-F is recommended for use:
– for diseases of the reproductive system, which are based on the processes of pathological cell proliferation;
– in order to normalize estrogen metabolism in estrogen-dependent diseases:
endometrial hyperplasia, uterine leiomyoma, uterine fibroids in combination with endometrial hyperplastic processes, endometriosis (including adenomyosis, endometrioid ovarian cysts);
– for diseases associated with HPV (cervical dysplasia, anogenital condylomas);
– in order to normalize estrogen metabolism during hormonal changes (puberty, perimenopause, etc.). Can be used for the prevention and correction of estrogen-dependent conditions from 12 years of age.
COMPOSITION
Mixture of cruciferous vegetables – 59.5% (238.0 mg), indole-3-carbinol – 22.5% (90.0 mg), antioxidant ascorbic acid – 12.5% (50.0 mg), calcium stearate – 3.0%, broccoli extract – 2.5% (10.0 mg).
DESCRIPTION OF EXISTING SUBSTANCES
Indole-3-carbinol (I3C) normalizes estrogen metabolism and prevents the development of estrogen-dependent diseases. Effective for disorders associated with hyperplasia in mammology, gynecology and andrology. Has a powerful antiviral effect.
I3S inhibits the synthesis of the proliferative metabolite 16α-ONE1, which, firmly binding to estrogen-dependent receptors, causes uncontrolled proliferative processes, being a carcinogen in relation to the reproductive organs.
I3S has a highly active antiproliferative effect, inhibits inflammation, growth and proliferation of transformed cells, neutralizes the action of growth factors that stimulate tumor development in hormone-dependent organs of the reproductive system; inhibits the effect of pro-inflammatory cytokines.
I3C prevents the synthesis of E7 protein in epithelial cells infected with human papillomavirus, including types 16 and 18, inhibiting the processes of malignancy. I3C activates the expression of antitumor defense genes BRCA. Has high antioxidant properties.
Use of Indole-3-carbinol in men.
In pathological conditions based on an increase in active dihydrotestosterone, which leads to diseases of the male reproductive system. Excessive synthesis of estrogen in the male body causes erectile dysfunction, decreased libido, depression, female obesity, and gynecomastia. Indole-3-carbinol is effective for normalizing the metabolism of testosterone and estrogen.
Vegetables of the mustard family are a source of active natural indole substances: ascorbigen, diindolylmethane, sulforaphane. The combined action of these substances reduces the risk of malignant processes in the human body.
Ascorbigen is a biologically active compound of the cruciferous family; when ascorbigen is combined with indole-3-carbinol, their effect is mutually enhanced.
Ascorbigen is a source of antioxidants that reduce free radical oxidation; helps strengthen blood vessels and immunity, prevents the absorption of toxins through the walls of the small and large intestines.
Diindolylmethane (DIM) is a compound formed by a combination of 2 molecules of indole-3-carbinol, the effectiveness of which is significantly increased when used simultaneously with I3S. DIM stimulates apoptosis of human papillomavirus (HPV)-infected and transformed cells, stimulates the expression of interferon-γ receptors, accelerates the elimination of human papillomavirus (HPV)-infected and transformed cells, and enhances the nonspecific immune response to infection. DIM normalizes the metabolism of estradiol in HPV-infected cells, preventing the formation of the carcinogenic estrogen metabolite (16-hydroxyestrone), which stimulates the expression of HPV oncogenes. By inhibiting the expression of the human papillomavirus E7 oncogene, DIM blocks the hormone-dependent pathological proliferation of HPV-infected cells.
Sulforaphane is a biologically active compound from plants of the cruciferous family that has antitumor and antibacterial effects. Indole-3-carbinol, ascorbigen and sulforaphane take part in the normalization of the enzyme system of the large and small intestines, and also enhance the detoxification function of the liver.
Broccoli extract is the leader in the content of indole-3-carbinol. Contains a large amount of selenium (a trace element with powerful antioxidant properties, improves the functioning of the cardiovascular system, liver and gastrointestinal tract, improves immunity, stimulates insulin production), vitamins C, A, group B, anti-ulcer vitamin U, microelements: potassium, calcium, phosphorus, iron, sodium.
Ascorbic acid (vitamin C) is an active participant in the regulation of redox processes in the body, regulates carbohydrate metabolism, blood clotting, tissue regeneration, reduces the permeability of the vascular wall, and has antiplatelet and pronounced antioxidant properties. Strengthens the detoxification and protein-forming function of the liver, increases the synthesis of prothrombin; increases the body’s resistance to infections, inhibits the formation of inflammatory mediators and allergic reactions – exhibits an antihistamine effect.
METHOD OF APPLICATION
1-2 capsules 2 times a day with meals, wash down with water. The course of admission is from 3 to 6 months. If necessary, the course can be repeated. The dose adjustment and duration of administration is determined by the doctor. Do not exceed the recommended daily intake. Before use, consultation with a doctor is recommended.
Age up to 12 years, pregnancy, breastfeeding, individual sensitivity to components. It is not recommended to take foods that reduce stomach acid at the same time.
PRECAUTIONS FOR USE
Age up to 12 years, pregnancy, breastfeeding, individual sensitivity to components. It is not recommended to take foods that reduce stomach acid at the same time.
KCAL / 100 G ENERGY VALUE
89 kcal
FOOD (NUTRITIONAL) VALUE OF 100 G PRODUCT
Proteins – 1.8 g, carbohydrates – 0,68 g, fats – 0,2 g.
ISSUE FORM
400 mg capsules.
SHELF LIFE
24 months
